The lab: Forslund group
In terms of individual diversity we have seven nationalities represented (five members from outside of Europe), 4+ of the letters in LGBTQ, and women making up two thirds of the lab. Discipline-wise we include clinicians, experimentalists and computational biologists (with the latter roughly 80% of the lab). We try to make the most synergy out of diversity as we can, and embrace win-win situations with collaborators whenever possible. Currently there are collaborations with e.g. Charité clinics of Paul, Scheibenbogen, Dechend, Siegmund, Opitz, Haghikia, Diefenbach, Worm, Beyer, Oevermann, Pieske, Spranger, Mall, Tacke and Buss, as well as clinicians elsewhere in Germany (e.g. Stumvoll in Leipzig, Viemann in Hannover, Gehring in Mainz, and the German Neonatal Network).
The position
Gender medicine, especially the role of sex hormone signalling on microbiome, metabolism, immune system and other factors, and the way this manifests in differential risk, manifestation and treatment efficacy in cardiovascular, metabolic, autoimmune and other diseases. The Emerald project will deal with observational studies of groups where hormone levels predictably change, including studies of the menstrual cycle in PMDD, conditions such as PCOS, menopause or pregnancy, and following transgender individuals throughout hormone replacement therapy. We further have access to useful animal models through collaborators.
Other positions
IDIBAPS#4 – Mechanisms involved in strenuous exercise-induced atrial myocardial fibrosis
IC#4 – The role polyglutamylation in tauopathic neurodegeneration
IC#3 – Evaluation of the efficiency of immunotherapy by tracing ctDNA in metastatic NSCLC and triple-negative breast cancer patients
IC#2 – New targetable vulnerabilities for the treatment of chemoresistant breast and ovarian BRCA1/2-mutated tumors
IDIBAPS#3 – Mechanisms involved in vascular inflammation/remodeling in systemic vasculitis
IDIBAPS#2 – Mechanisms and therapies for Myeloma, amyloidosis, macroglobulinemia and other gammapathies
IDIBAPS#1 – Developing and investigating computing, machine learning and physiological modelling for understanding each individual heart towards personalised medicine
BRIC#6 – Tumour evolution, heterogeneity, and understanding of the mutational processes leading to aggressive disease
IC#1 – The role of RNASE1 in lung metastatic niche establishment by breast cancer cells
MDC#3 – Neuromuscular and Cardiovascular Cell Biology
MDC#2 – Molecular and cellular basis of behavior
MDC#1 – Host-microbiome factors in cardiovascular disease
NKI#1 – Epigenetic regulation in hormone-driven cancers and therapy resistance
VIB#8 – Mechanisms of inflammation and associated tissue damage in musculoskeletal diseases
VIB#7 – Endothelial immunosuppressive mystery genes for alternative immunotherapy: artificial intelligence-driven target discovery and validation
VIB#6 – Cellular metabolism and metabolic regulation in cancer metastasis
VIB#5 – Unraveling the molecular mechanisms of neuronal degeneration in motor neuron diseases
VIB#4 – Identification of universal biomarkers of metastatic melanoma in CTCs
VIB#3 – Basic mechanisms of Alzheimer’s disease and neurodegeneration
VIB#2 – Integrative genomics to underpinning somatic evolution, tumour heterogeneity, and treatment resistance
VIB#1 – Medical biotechnology to improve hepatocellular carcinoma diagnostics
BRIC#5 – The impact of severe maternal respiratory tract infections on fetal brain development and offspring behavior
