The lab: Demengeot group
The research group, led by Jocelyne Demengeot, is concerned with those properties of the immune system that guarantee tissue integrity as well as tolerance to commensals and food antigens while maintaining the ability to mount efficient responses to infectious agents and some tumours. Rooted in this thematic is also the biological puzzle of phenotypic heterogeneity, the challenge of personalised medicine.
The research group approach the cellular and molecular bases of immune regulation through the analysis of various mouse models, notably of spontaneous or induced autoimmune and immuno-pathological inflammation.
Closer to the clinic, they interrogate the biological basis of the most extreme manifestations in autoimmune diseases and of the variable efficacy of immunotherapies.
Other positions
- IDIBAPS#4 – Mechanisms involved in strenuous exercise-induced atrial myocardial fibrosisDavid Brena2022-06-02T10:51:50+00:00
IDIBAPS#4 – Mechanisms involved in strenuous exercise-induced atrial myocardial fibrosis
- IC#4 – The role polyglutamylation in tauopathic neurodegenerationDavid Brena2022-05-18T16:35:32+00:00
IC#4 – The role polyglutamylation in tauopathic neurodegeneration
- IC#3 – Evaluation of the efficiency of immunotherapy by tracing ctDNA in metastatic NSCLC and triple-negative breast cancer patientsDavid Brena2022-05-18T16:17:43+00:00
IC#3 – Evaluation of the efficiency of immunotherapy by tracing ctDNA in metastatic NSCLC and triple-negative breast cancer patients
- IC#2 – New targetable vulnerabilities for the treatment of chemoresistant breast and ovarian BRCA1/2-mutated tumorsDavid Brena2022-05-25T10:09:18+00:00
IC#2 – New targetable vulnerabilities for the treatment of chemoresistant breast and ovarian BRCA1/2-mutated tumors
- IDIBAPS#3 – Mechanisms involved in vascular inflammation/remodeling in systemic vasculitisDavid Brena2022-05-17T10:38:48+00:00
IDIBAPS#3 – Mechanisms involved in vascular inflammation/remodeling in systemic vasculitis
- IDIBAPS#2 – Mechanisms and therapies for Myeloma, amyloidosis, macroglobulinemia and other gammapathiesDavid Brena2022-05-24T08:49:06+00:00
IDIBAPS#2 – Mechanisms and therapies for Myeloma, amyloidosis, macroglobulinemia and other gammapathies
- IDIBAPS#1 – Developing and investigating computing, machine learning and physiological modelling for understanding each individual heart towards personalised medicineDavid Brena2022-05-17T10:37:53+00:00
IDIBAPS#1 – Developing and investigating computing, machine learning and physiological modelling for understanding each individual heart towards personalised medicine
- BRIC#6 – Tumour evolution, heterogeneity, and understanding of the mutational processes leading to aggressive diseaseDavid Brena2022-05-12T16:57:52+00:00
BRIC#6 – Tumour evolution, heterogeneity, and understanding of the mutational processes leading to aggressive disease
- IC#1 – The role of RNASE1 in lung metastatic niche establishment by breast cancer cellsemerald_SCS2022-05-17T13:59:30+00:00
IC#1 – The role of RNASE1 in lung metastatic niche establishment by breast cancer cells
- MDC#3 – Neuromuscular and Cardiovascular Cell Biologyemerald_SCS2022-05-17T12:04:54+00:00
MDC#3 – Neuromuscular and Cardiovascular Cell Biology
- MDC#2 – Molecular and cellular basis of behavioremerald_SCS2022-05-17T12:05:10+00:00
MDC#2 – Molecular and cellular basis of behavior
- MDC#1 – Host-microbiome factors in cardiovascular diseaseemerald_SCS2022-05-17T12:05:25+00:00
MDC#1 – Host-microbiome factors in cardiovascular disease
- NKI#1 – Epigenetic regulation in hormone-driven cancers and therapy resistanceemerald_SCS2022-05-19T08:58:30+00:00
NKI#1 – Epigenetic regulation in hormone-driven cancers and therapy resistance
- VIB#8 – Mechanisms of inflammation and associated tissue damage in musculoskeletal diseasesemerald_SCS2022-05-16T20:44:33+00:00
VIB#8 – Mechanisms of inflammation and associated tissue damage in musculoskeletal diseases
- VIB#7 – Endothelial immunosuppressive mystery genes for alternative immunotherapy: artificial intelligence-driven target discovery and validationemerald_SCS2022-05-16T20:32:47+00:00
VIB#7 – Endothelial immunosuppressive mystery genes for alternative immunotherapy: artificial intelligence-driven target discovery and validation
- VIB#6 – Cellular metabolism and metabolic regulation in cancer metastasisemerald_SCS2022-05-18T08:52:10+00:00
VIB#6 – Cellular metabolism and metabolic regulation in cancer metastasis
- VIB#5 – Unraveling the molecular mechanisms of neuronal degeneration in motor neuron diseasesemerald_SCS2022-05-16T19:39:35+00:00
VIB#5 – Unraveling the molecular mechanisms of neuronal degeneration in motor neuron diseases
- VIB#4 – Identification of universal biomarkers of metastatic melanoma in CTCsemerald_SCS2022-05-18T08:43:51+00:00
VIB#4 – Identification of universal biomarkers of metastatic melanoma in CTCs
- VIB#3 – Basic mechanisms of Alzheimer’s disease and neurodegenerationemerald_SCS2022-05-16T19:54:56+00:00
VIB#3 – Basic mechanisms of Alzheimer’s disease and neurodegeneration
- VIB#2 – Integrative genomics to underpinning somatic evolution, tumour heterogeneity, and treatment resistanceemerald_SCS2022-05-15T23:07:12+00:00
VIB#2 – Integrative genomics to underpinning somatic evolution, tumour heterogeneity, and treatment resistance
- VIB#1 – Medical biotechnology to improve hepatocellular carcinoma diagnosticsemerald_SCS2022-05-24T08:33:04+00:00
VIB#1 – Medical biotechnology to improve hepatocellular carcinoma diagnostics
- BRIC#5 – The impact of severe maternal respiratory tract infections on fetal brain development and offspring behavioremerald_SCS2022-05-19T18:49:58+00:00
BRIC#5 – The impact of severe maternal respiratory tract infections on fetal brain development and offspring behavior
- BRIC#7 – Understanding and overcoming drug resistance in acute myeloid leukemiaemerald_SCS2022-05-24T08:43:03+00:00
BRIC#7 – Understanding and overcoming drug resistance in acute myeloid leukemia
